Necrostatin-1 enhances the resolution of inflammation by specifically inducing neutrophil apoptosis

Neutrophils play a central role in innate immunity and are rapidly recruited to sites of infection and injury. Neutrophil apoptosis is essential for the successful resolution of inflammation. Necrostatin-1 (Nec-1,methyl-thiohydantoin-tryptophan (MTH-Trp)), is a potent and specific inhibitor of necro...

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Bibliographic Details
Main Authors: Jie, Hongyu, He, Yi, Huang, Xuechan, Zhou, Qingyou, Han, Yanping, Li, Xing, Bai, Yongkun, Sun, Erwei
Format: Online
Language:English
Published: Impact Journals LLC 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991389/