Direct visualization of both DNA and RNA quadruplexes in human cells via an uncommon spectroscopic method

Guanine-rich DNA or RNA sequences can fold into higher-order, four-stranded structures termed quadruplexes that are suspected to play pivotal roles in cellular mechanisms including the control of the genome integrity and gene expression. However, the biological relevance of quadruplexes is still a m...

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Bibliographic Details
Main Authors: Laguerre, Aurélien, Wong, Judy M. Y., Monchaud, David
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989495/