How Good Are Statistical Models at Approximating Complex Fitness Landscapes?

Fitness landscapes determine the course of adaptation by constraining and shaping evolutionary trajectories. Knowledge of the structure of a fitness landscape can thus predict evolutionary outcomes. Empirical fitness landscapes, however, have so far only offered limited insight into real-world quest...

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Bibliographic Details
Main Authors: du Plessis, Louis, Leventhal, Gabriel E., Bonhoeffer, Sebastian
Format: Online
Language:English
Published: Oxford University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989103/