Pharmacokinetic and pharmacodynamic interactions between metformin and a novel dipeptidyl peptidase-4 inhibitor, evogliptin, in healthy subjects
Evogliptin is a newly developed dipeptidyl peptidase-4 (DPP-4) inhibitor, which is expected to be combined with metformin for treating type 2 diabetes mellitus. We investigated the potential pharmacokinetic and pharmacodynamic interactions between evogliptin and metformin. A randomized, open-label,...
Main Authors: | , , , , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Dove Medical Press
2016
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986685/ |