Association between TLR4 and PTEN Involved in LPS-TLR4 Signaling Response

In this study, we explored the potential mechanisms of how PTEN regulating LPS induced TLR4 signaling pathway. The initial findings from ELISA demonstrate that PTEN influences TNF-α secretion by its lipid phosphatase activity. Subsequently, western blot, immunoprecipitation assay, and immunofluoresc...

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Bibliographic Details
Main Authors: Yin, Huahua, Tan, Yan, Wu, Xiaofeng, Yan, Hong, Liu, Feng, Yao, Yuanzhang, Jiang, Jianxin, Wan, Qi, Li, Lei
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985570/