Cofilin-mediated actin dynamics promotes actin bundle formation during Drosophila bristle development

Cofilin, the actin disassembly factor, regulates actin bundle formation by promoting a local reservoir of a high level of G-actin and limiting the size of a distinct actin-myosin network. Cofilin also regulates the positioning of actin bundles in the Drosophila bristle and prevents incorrect assembl...

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Bibliographic Details
Main Authors: Wu, Jing, Wang, Heng, Guo, Xuan, Chen, Jiong
Format: Online
Language:English
Published: The American Society for Cell Biology 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985257/