Toxic Accumulation of LPS Pathway Intermediates Underlies the Requirement of LpxH for Growth of Acinetobacter baumannii ATCC 19606

Toxic Accumulation of LPS Pathway Intermediates Underlies the Requirement of LpxH for Growth of Acinetobacter baumannii ATCC 19606

The lipid A moiety of lipopolysaccharide (LPS) is the main constituent of the outer leaflet of the Gram-negative bacterial outer membrane (OM) and is essential in many Gram-negative pathogens. An exception is Acinetobacter baumannii ATCC 19606, where mutants lacking enzymes occurring early in lipid...

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Bibliographic Details
Main Authors: Richie, Daryl L., Takeoka, Kenneth T., Bojkovic, Jade, Metzger, Louis E., Rath, Christopher M., Sawyer, William S., Wei, Jun-Rong, Dean, Charles R.
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985137/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985137/

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