The Role of mGlu Receptors in Hippocampal Plasticity Deficits in Neurological and Psychiatric Disorders: Implications for Allosteric Modulators as Novel Therapeutic Strategies

Long-term potentiation (LTP) and long-term depression (LTD) are two distinct forms of synaptic plasticity that have been extensively characterized at the Schaffer collateral-CA1 (SC-CA1) synapse and the mossy fiber (MF)-CA3 synapse within the hippocampus, and are postulated to be the molecular under...

Full description

Bibliographic Details
Main Authors: Senter, Rebecca K., Ghoshal, Ayan, Walker, Adam G., Xiang, Zixiu, Niswender, Colleen M., Conn, P. Jeffrey
Format: Online
Language:English
Published: Bentham Science Publishers 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983746/