H3K27me3 Does Not Orchestrate the Expression of Lineage-Specific Markers in hESC-Derived Hepatocytes In Vitro

H3K27me3 Does Not Orchestrate the Expression of Lineage-Specific Markers in hESC-Derived Hepatocytes In Vitro

Although pluripotent stem cells can be differentiated into the hepatocyte lineages, such cells retain an immature phenotype. As the chromatin state of regulatory regions controls spatiotemporal gene expression during development, we evaluated changes in epigenetic histone marks in lineage-specific g...

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Bibliographic Details
Main Authors: Vanhove, Jolien, Pistoni, Mariaelena, Welters, Marc, Eggermont, Kristel, Vanslembrouck, Veerle, Helsen, Nicky, Boon, Ruben, Najimi, Mustapha, Sokal, Etienne, Collas, Philippe, Voncken, J. Willem, Verfaillie, Catherine M.
Format: Online
Language:English
Published: Elsevier 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982990/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982990/

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