MIF Plays a Key Role in Regulating Tissue-Specific Chondro-Osteogenic Differentiation Fate of Human Cartilage Endplate Stem Cells under Hypoxia

Degenerative cartilage endplate (CEP) shows decreased chondrification and increased ossification. Cartilage endplate stem cells (CESCs), with the capacity for chondro-osteogenic differentiation, are responsible for CEP restoration. CEP is avascular and hypoxic, while the physiological hypoxia is dis...

Full description

Bibliographic Details
Main Authors: Yao, Yuan, Deng, Qiyue, Song, Weilin, Zhang, Huiyu, Li, Yuanjing, Yang, Yang, Fan, Xin, Liu, Minghan, Shang, Jin, Sun, Chao, Tang, Yu, Jin, Xiangting, Liu, Huan, Huang, Bo, Zhou, Yue
Format: Online
Language:English
Published: Elsevier 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982989/