Rapid and Efficient Stable Gene Transfer to Mesenchymal Stromal Cells Using a Modified Foamy Virus Vector

Rapid and Efficient Stable Gene Transfer to Mesenchymal Stromal Cells Using a Modified Foamy Virus Vector

Mesenchymal stromal cells (MSCs) hold great promise for regenerative medicine. Stable ex vivo gene transfer to MSCs could improve the outcome and scope of MSC therapy, but current vectors require multiple rounds of transduction, involve genotoxic viral promoters and/or the addition of cytotoxic cati...

Full description

Bibliographic Details
Main Authors: Sweeney, Nathan Paul, Regan, Cathy, Liu, Jiahui, Galleu, Antonio, Dazzi, Francesco, Lindemann, Dirk, Rupar, Charles Anthony, McClure, Myra Olga
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982542/

Similar Items

Similar Items