The catalytic power of magnesium chelatase: a benchmark for the AAA + ATPases
In the first committed reaction of chlorophyll biosynthesis, magnesium chelatase couples ATP hydrolysis to the thermodynamically unfavorable Mg2+ insertion into protoporphyrin IX (ΔG°′ of circa 25–33 kJ·mol−1). We explored the thermodynamic constraints on magnesium chelatase and demonstrate the effe...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
John Wiley and Sons Inc.
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982103/ |