The catalytic power of magnesium chelatase: a benchmark for the AAA + ATPases

In the first committed reaction of chlorophyll biosynthesis, magnesium chelatase couples ATP hydrolysis to the thermodynamically unfavorable Mg2+ insertion into protoporphyrin IX (ΔG°′ of circa 25–33 kJ·mol−1). We explored the thermodynamic constraints on magnesium chelatase and demonstrate the effe...

Full description

Bibliographic Details
Main Authors: Adams, Nathan B. P., Brindley, Amanda A., Hunter, C. Neil, Reid, James D.
Format: Online
Language:English
Published: John Wiley and Sons Inc. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982103/