Transient Canonical Wnt Stimulation Enriches Human Bone Marrow Mononuclear Cell Isolates for Osteoprogenitors

Activation of the canonical Wnt signaling pathway is an attractive anabolic therapeutic strategy for bone. Emerging data suggest that activation of the Wnt signaling pathway promotes bone mineral accrual in osteoporotic patients. The effect of Wnt stimulation in fracture healing is less clear as Wnt...

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Bibliographic Details
Main Authors: Janeczek, Agnieszka A., Tare, Rahul S., Scarpa, Edoardo, Moreno‐Jimenez, Ines, Rowland, Caroline A., Jenner, Dominic, Newman, Tracey A., Oreffo, Richard O. C., Evans, Nicholas D.
Format: Online
Language:English
Published: John Wiley and Sons Inc. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981914/