Transcriptomic variation of pharmacogenes in multiple human tissues and lymphoblastoid cell lines

Transcriptomic variation of pharmacogenes in multiple human tissues and lymphoblastoid cell lines

Variation in the expression level and activity of genes involved in drug disposition and action (‘pharmacogenes') can affect drug response and toxicity, especially when in tissues of pharmacological importance. Previous studies have relied primarily on microarrays to understand gene expression...

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Bibliographic Details
Main Authors: Chhibber, A, French, C E, Yee, S W, Gamazon, E R, Theusch, E, Qin, X, Webb, A, Papp, A C, Wang, A, Simmons, C Q, Konkashbaev, A, Chaudhry, A S, Mitchel, K, Stryke, D, Ferrin, T E, Weiss, S T, Kroetz, D L, Sadee, W, Nickerson, D A, Krauss, R M, George, A L, Schuetz, E G, Medina, M W, Cox, N J, Scherer, S E, Giacomini, K M, Brenner, S E
Format: Online
Language:English
Published: Nature Publishing Group 2017
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980276/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980276/

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