The 4p16.3 Parkinson Disease Risk Locus Is Associated with GAK Expression and Genes Involved with the Synaptic Vesicle Membrane

The 4p16.3 Parkinson Disease Risk Locus Is Associated with GAK Expression and Genes Involved with the Synaptic Vesicle Membrane

Genome-wide association studies (GWAS) have identified the GAK/DGKQ/IDUA region on 4p16.3 among the top three risk loci for Parkinson’s disease (PD), but the specific gene and risk mechanism are unclear. Here, we report transcripts containing the 3’ clathrin-binding domain of GAK identified by RNA d...

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Bibliographic Details
Main Authors: Nagle, Michael W., Latourelle, Jeanne C., Labadorf, Adam, Dumitriu, Alexandra, Hadzi, Tiffany C., Beach, Thomas G., Myers, Richard H.
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980018/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980018/

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