miR-6734 Up-Regulates p21 Gene Expression and Induces Cell Cycle Arrest and Apoptosis in Colon Cancer Cells

Recently, microRNAs have been implicated in the regulation of gene expression in terms of both gene silencing and gene activation. Here, we investigated the effects of miR-6734, which has a sequence homology with a specific region of p21WAF1/CIP1 (p21) promoter, on cancer cell growth and the mechani...

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Bibliographic Details
Main Authors: Kang, Moo Rim, Park, Ki Hwan, Yang, Jeong-Ook, Lee, Chang Woo, Oh, Soo Jin, Yun, Jieun, Lee, Myeong Youl, Han, Sang-Bae, Kang, Jong Soon
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979902/