Is Transthyretin a Regulator of Ubc9 SUMOylation?

Ageing and mutations of transthyretin (TTR), the thyroid hormones and retinol transporting protein lead to amyloidosis by destabilizing the structure of TTR. Because protein structure is regulated through posttranslational modifications, we investigated the Small Ubiquitin-like Modifier (SUMO)ylatio...

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Bibliographic Details
Main Authors: Wieczorek, Elżbieta, Kędracka–Krok, Sylwia, Sołtys, Katarzyna, Jankowska, Urszula, Hołubowicz, Rafał, Seliga, Justyna, Ożyhar, Andrzej
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976990/