Functional screening implicates miR-371-3p and peroxiredoxin 6 in reversible tolerance to cancer drugs

Acquired resistance to cancer drug therapies almost always occurs in advanced-stage patients even following a significant response to treatment. In addition to mutational mechanisms, various non-mutational resistance mechanisms have now been recognized. We previously described a chromatin-mediated s...

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Bibliographic Details
Main Authors: Sahu, Nisebita, Stephan, Jean-Philippe, Cruz, Darlene Dela, Merchant, Mark, Haley, Benjamin, Bourgon, Richard, Classon, Marie, Settleman, Jeff
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976141/