Bone Turnover Markers and Osteoprotegerin in Uncomplicated Pregnancy

Bone Turnover Markers and Osteoprotegerin in Uncomplicated Pregnancy

Although calcium metabolism during pregnancy is well described the mechanisms involved in bone metabolism are not quite clear. Increase of osteoprotegerin (OPG) with elevated bone turnover is supposed to be a homeostatic mechanism limiting bone loss. The aim of the study was to assess bone turnover...

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Main Authors: Styczynska, Hanna, Lis, Kinga, Sobanska, Izabela, Pater, Agnieszka, Pollak, Joanna, Mankowska, Aneta
Format: Online
Language:English
Published: The Communications and Publications Division (CPD) of the IFCC 2009
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975284/
id pubmed-4975284
recordtype oai_dc
spelling pubmed-49752842016-09-28 Bone Turnover Markers and Osteoprotegerin in Uncomplicated Pregnancy Styczynska, Hanna Lis, Kinga Sobanska, Izabela Pater, Agnieszka Pollak, Joanna Mankowska, Aneta Research Article Although calcium metabolism during pregnancy is well described the mechanisms involved in bone metabolism are not quite clear. Increase of osteoprotegerin (OPG) with elevated bone turnover is supposed to be a homeostatic mechanism limiting bone loss. The aim of the study was to assess bone turnover in pregnancy in relation to serum osteoprotegerin level. Osteocalcin (OC), beta-crosslaps (CTx), OPG, vitamin 25 OH D3, parathormone (PTH), and calcium (Ca) were determined in 30 healthy women at 1st and at 3rd trimester of pregnancy and 27 healthy age-matched non pregnant women. The Communications and Publications Division (CPD) of the IFCC 2009-01-20 /pmc/articles/PMC4975284/ /pubmed/27683317 Text en Copyright © 2008 International Federation of Clinical Chemistry and Laboratory Medicine (IFCC). All rights reserved. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Styczynska, Hanna
Lis, Kinga
Sobanska, Izabela
Pater, Agnieszka
Pollak, Joanna
Mankowska, Aneta
spellingShingle Styczynska, Hanna
Lis, Kinga
Sobanska, Izabela
Pater, Agnieszka
Pollak, Joanna
Mankowska, Aneta
Bone Turnover Markers and Osteoprotegerin in Uncomplicated Pregnancy
author_facet Styczynska, Hanna
Lis, Kinga
Sobanska, Izabela
Pater, Agnieszka
Pollak, Joanna
Mankowska, Aneta
author_sort Styczynska, Hanna
title Bone Turnover Markers and Osteoprotegerin in Uncomplicated Pregnancy
title_short Bone Turnover Markers and Osteoprotegerin in Uncomplicated Pregnancy
title_full Bone Turnover Markers and Osteoprotegerin in Uncomplicated Pregnancy
title_fullStr Bone Turnover Markers and Osteoprotegerin in Uncomplicated Pregnancy
title_full_unstemmed Bone Turnover Markers and Osteoprotegerin in Uncomplicated Pregnancy
title_sort bone turnover markers and osteoprotegerin in uncomplicated pregnancy
description Although calcium metabolism during pregnancy is well described the mechanisms involved in bone metabolism are not quite clear. Increase of osteoprotegerin (OPG) with elevated bone turnover is supposed to be a homeostatic mechanism limiting bone loss. The aim of the study was to assess bone turnover in pregnancy in relation to serum osteoprotegerin level. Osteocalcin (OC), beta-crosslaps (CTx), OPG, vitamin 25 OH D3, parathormone (PTH), and calcium (Ca) were determined in 30 healthy women at 1st and at 3rd trimester of pregnancy and 27 healthy age-matched non pregnant women.
publisher The Communications and Publications Division (CPD) of the IFCC
publishDate 2009
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975284/
_version_ 1613622437717475328

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