Cutaneous wound healing through paradoxical MAPK activation by BRAF inhibitors

Cutaneous wound healing through paradoxical MAPK activation by BRAF inhibitors

BRAF inhibitors are highly effective therapies for the treatment of BRAFV600-mutated melanoma, with the main toxicity being a variety of hyperproliferative skin conditions due to paradoxical activation of the mitogen-activated protein kinase (MAPK) pathway in BRAF wild-type cells. Most of these hype...

Full description

Bibliographic Details
Main Authors: Escuin-Ordinas, Helena, Li, Shuoran, Xie, Michael W., Sun, Lu, Hugo, Willy, Huang, Rong Rong, Jiao, Jing, de-Faria, Felipe Meira, Realegeno, Susan, Krystofinski, Paige, Azhdam, Ariel, Komenan, Sara Marie D., Atefi, Mohammad, Comin-Anduix, Begoña, Pellegrini, Matteo, Cochran, Alistair J., Modlin, Robert L., Herschman, Harvey R., Lo, Roger S., McBride, William H., Segura, Tatiana, Ribas, Antoni
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974650/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974650/

Similar Items