Lkb1 controls brown adipose tissue growth and thermogenesis by regulating the intracellular localization of CRTC3

Lkb1 controls brown adipose tissue growth and thermogenesis by regulating the intracellular localization of CRTC3

Brown adipose tissue (BAT) dissipates energy through Ucp1-mediated uncoupled respiration and its activation may represent a therapeutic strategy to combat obesity. Here we show that Lkb1 controls BAT expansion and UCP1 expression in mice. We generate adipocyte-specific Lkb1 knockout mice and show th...

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Bibliographic Details
Main Authors: Shan, Tizhong, Xiong, Yan, Zhang, Pengpeng, Li, Zhiguo, Jiang, Qingyang, Bi, Pengpeng, Yue, Feng, Yang, Gongshe, Wang, Yizhen, Liu, Xiaoqi, Kuang, Shihuan
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974456/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974456/

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