Ribose 5-phosphate isomerase inhibits LC3 processing and basal autophagy

Autophagy and cellular metabolism are tightly linked processes, but how individual metabolic enzymes regulate the process of autophagy is not well understood. This study implicates ribose-5-phosphate isomerase (RPIA), a key regulator of the pentose phosphate pathway, in the control of autophagy. We...

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Bibliographic Details
Main Authors: Heintze, Jacob, Costa, Joana R., Weber, Melanie, Ketteler, Robin
Format: Online
Language:English
Published: Elsevier Science Ltd 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973805/