Regulation of Retinoic Acid Inducible Gene-I (RIG-I) Activation by the Histone Deacetylase 6
Retinoic acid inducible gene-I (RIG-I) is a cytosolic pathogen recognition receptor that initiates the immune response against many RNA viruses. Upon RNA ligand binding, RIG-I undergoes a conformational change facilitating its homo-oligomerization and activation that results in its translocation fro...
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Elsevier
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972567/ |