Reversible lysine acetylation is involved in DNA replication initiation by regulating activities of initiator DnaA in Escherichia coli

The regulation of chromosomal replication is critical and the activation of DnaA by ATP binding is a key step in replication initiation. However, it remains unclear whether and how the process of ATP-binding to DnaA is regulated. Here, we show that DnaA can be acetylated, and its acetylation level v...

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Bibliographic Details
Main Authors: Zhang, Qiufen, Zhou, Aiping, Li, Shuxian, Ni, Jinjing, Tao, Jing, Lu, Jie, Wan, Baoshan, Li, Shuai, Zhang, Jian, Zhao, Shimin, Zhao, Guo-Ping, Shao, Feng, Yao, Yu-Feng
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971506/