Gene aberrations for precision medicine against lung adenocarcinoma

Lung adenocarcinoma (LADC), the most frequent histological type of lung cancer, is often triggered by an aberration in a driver oncogene in tumor cells. Examples of such aberrations are EGFR mutation and ALK fusion. Lung adenocarcinoma harboring such mutations can be treated with anticancer drugs th...

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Bibliographic Details
Main Authors: Saito, Motonobu, Shiraishi, Kouya, Kunitoh, Hideo, Takenoshita, Seiichi, Yokota, Jun, Kohno, Takashi
Format: Online
Language:English
Published: John Wiley and Sons Inc. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968599/