Radionuclide synovectomy – essentials for rheumatologists

Radionuclide synovectomy – essentials for rheumatologists

Radionuclide synovectomy is a minimally invasive method of treating persistent joint inflammation. It involves intra-articular injection of radioactive colloids which induce necrosis and fibrosis of hypertrophic synovial membrane. The most common indication for radiosynovectomy is rheumatoid arthrit...

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Main Authors: Chojnowski, Marek M., Felis-Giemza, Anna, Kobylecka, Małgorzata
Format: Online
Language:English
Published: Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji w Warszawie 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967977/
id pubmed-4967977
recordtype oai_dc
spelling pubmed-49679772016-08-08 Radionuclide synovectomy – essentials for rheumatologists Chojnowski, Marek M. Felis-Giemza, Anna Kobylecka, Małgorzata Review Paper Radionuclide synovectomy is a minimally invasive method of treating persistent joint inflammation. It involves intra-articular injection of radioactive colloids which induce necrosis and fibrosis of hypertrophic synovial membrane. The most common indication for radiosynovectomy is rheumatoid arthritis, although patients with seronegative spondyloarthropathies, unclassified arthritis, haemophilic arthropathy and other less common arthropathies can also benefit from this method. Radiosynovectomy is safe, well tolerated and efficacious. About 70–80% of patients respond well to the therapy. However, the therapeutic effects are considerably worse in patients with co-existent osteoarthritis and advanced joint degeneration. Despite its advantages, radionuclide synovectomy is not performed as often as it could be, so greater knowledge and understanding of this method are needed. The authors present the most important facts about radiosynovectomy that may help rheumatologists in their daily clinical practice. Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji w Warszawie 2016-07-18 2016 /pmc/articles/PMC4967977/ /pubmed/27504020 http://dx.doi.org/10.5114/reum.2016.61210 Text en Copyright © Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji w Warszawie 2016 http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Chojnowski, Marek M.
Felis-Giemza, Anna
Kobylecka, Małgorzata
spellingShingle Chojnowski, Marek M.
Felis-Giemza, Anna
Kobylecka, Małgorzata
Radionuclide synovectomy – essentials for rheumatologists
author_facet Chojnowski, Marek M.
Felis-Giemza, Anna
Kobylecka, Małgorzata
author_sort Chojnowski, Marek M.
title Radionuclide synovectomy – essentials for rheumatologists
title_short Radionuclide synovectomy – essentials for rheumatologists
title_full Radionuclide synovectomy – essentials for rheumatologists
title_fullStr Radionuclide synovectomy – essentials for rheumatologists
title_full_unstemmed Radionuclide synovectomy – essentials for rheumatologists
title_sort radionuclide synovectomy – essentials for rheumatologists
description Radionuclide synovectomy is a minimally invasive method of treating persistent joint inflammation. It involves intra-articular injection of radioactive colloids which induce necrosis and fibrosis of hypertrophic synovial membrane. The most common indication for radiosynovectomy is rheumatoid arthritis, although patients with seronegative spondyloarthropathies, unclassified arthritis, haemophilic arthropathy and other less common arthropathies can also benefit from this method. Radiosynovectomy is safe, well tolerated and efficacious. About 70–80% of patients respond well to the therapy. However, the therapeutic effects are considerably worse in patients with co-existent osteoarthritis and advanced joint degeneration. Despite its advantages, radionuclide synovectomy is not performed as often as it could be, so greater knowledge and understanding of this method are needed. The authors present the most important facts about radiosynovectomy that may help rheumatologists in their daily clinical practice.
publisher Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji w Warszawie
publishDate 2016
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967977/
_version_ 1613618505961177088

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