Mature dendritic cells cause Th17/Treg imbalance by secreting TGF-β1 and IL-6 in the pathogenesis of experimental autoimmune encephalomyelitis

Mature dendritic cells cause Th17/Treg imbalance by secreting TGF-β1 and IL-6 in the pathogenesis of experimental autoimmune encephalomyelitis

Multiple sclerosis (MS) is generally acknowledged to be an autoimmune disease, but its etiology remains unknown. The most intensively studied animal model of MS is experimental autoimmune encephalomyelitis (EAE). Dendritic cells (DCs), the professional antigen presenting cells (APCs), have gained in...

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Bibliographic Details
Main Authors: Lu, Pingxia, Cao, Yingping, Wang, Meihua, Zheng, Peizheng, Hou, Juan, Zhu, Chanhong, Hu, Jianda
Format: Online
Language:English
Published: Polish Society of Experimental and Clinical Immunology 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967648/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967648/

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