The expanding regulatory universe of p53 in gastrointestinal cancer
Tumor suppresser gene TP53 is one of the most frequently deleted or mutated genes in gastrointestinal cancers. As a transcription factor, p53 regulates a number of important protein coding genes to control cell cycle, cell death, DNA damage/repair, stemness, differentiation and other key cellular fu...
| Main Authors: | , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
F1000Research
2016
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963207/ |