Crude Preparations of Helicobacter pylori Outer Membrane Vesicles Induce Upregulation of Heme Oxygenase-1 via Activating Akt-Nrf2 and mTOR–IκB Kinase–NF-κB Pathways in Dendritic Cells
Helicobacter pylori sheds outer membrane vesicles (OMVs) that contain many surface elements of bacteria. Dendritic cells (DCs) play a major role in directing the nature of adaptive immune responses against H. pylori, and heme oxygenase-1 (HO-1) has been implicated in regulating function of DCs. In a...
Main Authors: | , , , , , , |
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Format: | Online |
Language: | English |
Published: |
American Society for Microbiology
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962631/ |