Identification of novel bacterial DNA gyrase inhibitors: An in silico study
Owing to essential role in bacterial survival, DNA gyrase has been exploited as a validated drug target. However, rapidly emerging resistance to gyrase-targeted drugs such as widely utilized fluoroquinolones reveals the necessity to develop novel compounds with new mechanism of actions against this...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
Medknow Publications & Media Pvt Ltd
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962306/ |