Identification of novel bacterial DNA gyrase inhibitors: An in silico study

Owing to essential role in bacterial survival, DNA gyrase has been exploited as a validated drug target. However, rapidly emerging resistance to gyrase-targeted drugs such as widely utilized fluoroquinolones reveals the necessity to develop novel compounds with new mechanism of actions against this...

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Bibliographic Details
Main Authors: Rahimi, Hamzeh, Najafi, Ali, Eslami, Habib, Negahdari, Babak, Moghaddam, Mehrdad Moosazadeh
Format: Online
Language:English
Published: Medknow Publications & Media Pvt Ltd 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962306/