Chronic UVB-irradiation actuates perpetuated dermal matrix remodeling in female mice: Protective role of estrogen

Chronic UVB-exposure and declined estradiol production after menopause represent important factors leading to extrinsic and intrinsic aging, respectively. Remodeling of the extracellular matrix (ECM) plays a crucial role in both responses. Whether the dermal ECM is able to recover after cessation of...

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Bibliographic Details
Main Authors: Röck, Katharina, Joosse, Simon Andreas, Müller, Julia, Heinisch, Nina, Fuchs, Nicola, Meusch, Michael, Zipper, Petra, Reifenberger, Julia, Pantel, Klaus, Fischer, Jens Walter
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962040/