Inhibition of TLR4 Signalling-Induced Inflammation Attenuates Secondary Injury after Diffuse Axonal Injury in Rats

Increasing evidence suggests that secondary injury after diffuse axonal injury (DAI) damages more axons than the initial insult, but the underlying mechanisms of this phenomenon are not fully understood. Recent studies show that toll-like receptor 4 (TLR4) plays a critical role in promoting adaptive...

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Bibliographic Details
Main Authors: Zhao, Yonglin, Zhao, Yahui, Zhang, Ming, Zhao, Junjie, Ma, Xudong, Huang, Tingqin, Pang, Honggang, Li, Jiaxi, Song, Jinning
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961816/