Object vision to hand action in macaque parietal, premotor, and motor cortices
Grasping requires translating object geometries into appropriate hand shapes. How the brain computes these transformations is currently unclear. We investigated three key areas of the macaque cortical grasping circuit with microelectrode arrays and found cooperative but anatomically separated visual...
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| Format: | Online |
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eLife Sciences Publications, Ltd
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961460/ |
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pubmed-49614602016-07-28 Object vision to hand action in macaque parietal, premotor, and motor cortices Schaffelhofer, Stefan Scherberger, Hansjörg Neuroscience Grasping requires translating object geometries into appropriate hand shapes. How the brain computes these transformations is currently unclear. We investigated three key areas of the macaque cortical grasping circuit with microelectrode arrays and found cooperative but anatomically separated visual and motor processes. The parietal area AIP operated primarily in a visual mode. Its neuronal population revealed a specialization for shape processing, even for abstract geometries, and processed object features ultimately important for grasping. Premotor area F5 acted as a hub that shared the visual coding of AIP only temporarily and switched to highly dominant motor signals towards movement planning and execution. We visualize these non-discrete premotor signals that drive the primary motor cortex M1 to reflect the movement of the grasping hand. Our results reveal visual and motor features encoded in the grasping circuit and their communication to achieve transformation for grasping. eLife Sciences Publications, Ltd 2016-07-26 /pmc/articles/PMC4961460/ /pubmed/27458796 http://dx.doi.org/10.7554/eLife.15278 Text en © 2016, Schaffelhofer et al http://creativecommons.org/licenses/by/4.0/ This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Schaffelhofer, Stefan Scherberger, Hansjörg |
| spellingShingle |
Schaffelhofer, Stefan Scherberger, Hansjörg Object vision to hand action in macaque parietal, premotor, and motor cortices |
| author_facet |
Schaffelhofer, Stefan Scherberger, Hansjörg |
| author_sort |
Schaffelhofer, Stefan |
| title |
Object vision to hand action in macaque parietal, premotor, and motor cortices |
| title_short |
Object vision to hand action in macaque parietal, premotor, and motor cortices |
| title_full |
Object vision to hand action in macaque parietal, premotor, and motor cortices |
| title_fullStr |
Object vision to hand action in macaque parietal, premotor, and motor cortices |
| title_full_unstemmed |
Object vision to hand action in macaque parietal, premotor, and motor cortices |
| title_sort |
object vision to hand action in macaque parietal, premotor, and motor cortices |
| description |
Grasping requires translating object geometries into appropriate hand shapes. How the brain computes these transformations is currently unclear. We investigated three key areas of the macaque cortical grasping circuit with microelectrode arrays and found cooperative but anatomically separated visual and motor processes. The parietal area AIP operated primarily in a visual mode. Its neuronal population revealed a specialization for shape processing, even for abstract geometries, and processed object features ultimately important for grasping. Premotor area F5 acted as a hub that shared the visual coding of AIP only temporarily and switched to highly dominant motor signals towards movement planning and execution. We visualize these non-discrete premotor signals that drive the primary motor cortex M1 to reflect the movement of the grasping hand. Our results reveal visual and motor features encoded in the grasping circuit and their communication to achieve transformation for grasping. |
| publisher |
eLife Sciences Publications, Ltd |
| publishDate |
2016 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961460/ |
| _version_ |
1613615345325572096 |