Self-assembly Controls Self-cleavage of HHR from ASBVd (−): a Combined SANS and Modeling Study

In the Avocado Sunblotch Viroid (ASBVd: 249-nt) from the Avsunviroidae family, a symmetric rolling-circle replication operates through an autocatalytic mechanism mediated by hammerhead ribozymes (HHR) embedded in both polarity strands. The concatenated multimeric ASBVd (+) and ASBVd (−) RNAs thus ge...

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Bibliographic Details
Main Authors: Leclerc, Fabrice, Zaccai, Giuseppe, Vergne, Jacques, Řìhovà, Martina, Martel, Anne, Maurel, Marie-Christine
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960562/