Apolipoprotein L1 Variant Associated with Increased Susceptibility to Trypanosome Infection

Apolipoprotein L1 Variant Associated with Increased Susceptibility to Trypanosome Infection

African trypanosomes, except Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense, which cause human African trypanosomiasis, are lysed by the human serum protein apolipoprotein L1 (ApoL1). These two subspecies can resist human ApoL1 because they express the serum resistance proteins T. b...

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Bibliographic Details
Main Authors: Cuypers, Bart, Lecordier, Laurence, Meehan, Conor J., Van den Broeck, Frederik, Imamura, Hideo, Büscher, Philippe, Dujardin, Jean-Claude, Laukens, Kris, Schnaufer, Achim, Dewar, Caroline, Lewis, Michael, Balmer, Oliver, Azurago, Thomas, Kyei-Faried, Sardick, Ohene, Sally-Ann, Duah, Boateng, Homiah, Prince, Mensah, Ebenezer Kofi, Anleah, Francis, Franco, Jose Ramon, Pays, Etienne, Deborggraeve, Stijn
Format: Online
Language:English
Published: American Society for Microbiology 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959518/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959518/

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