A novel algorithm for detecting multiple covariance and clustering of biological sequences

Single genetic mutations are always followed by a set of compensatory mutations. Thus, multiple changes commonly occur in biological sequences and play crucial roles in maintaining conformational and functional stability. Although many methods are available to detect single mutations or covariant pa...

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Bibliographic Details
Main Authors: Shen, Wei, Li, Yan
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958985/