CEP295 interacts with microtubules and is required for centriole elongation

Centriole duplication is a tightly ordered process during which procentrioles are assembled in G1-S and elongate during S and G2. Here, we show that human CEP295 (Drosophila Ana1) is not essential for initial cartwheel assembly, but is required to build distal half centrioles during S and G2. Using...

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Bibliographic Details
Main Authors: Chang, Ching-Wen, Hsu, Wen-Bin, Tsai, Jhih-Jie, Tang, Chieh-Ju C., Tang, Tang K.
Format: Online
Language:English
Published: The Company of Biologists Ltd 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958302/