αT-Catenin Is a Constitutive Actin-binding α-Catenin That Directly Couples the Cadherin·Catenin Complex to Actin Filaments*

αT-Catenin Is a Constitutive Actin-binding α-Catenin That Directly Couples the Cadherin·Catenin Complex to Actin Filaments*

α-Catenin is the primary link between the cadherin·catenin complex and the actin cytoskeleton. Mammalian αE-catenin is allosterically regulated: the monomer binds the β-catenin·cadherin complex, whereas the homodimer does not bind β-catenin but interacts with F-actin. As part of the cadherin·catenin...

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Bibliographic Details
Main Authors: Wickline, Emily D., Dale, Ian W., Merkel, Chelsea D., Heier, Jonathon A., Stolz, Donna B., Kwiatkowski, Adam V.
Format: Online
Language:English
Published: American Society for Biochemistry and Molecular Biology 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957052/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957052/

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