Anesthetic Sevoflurane Causes Rho-Dependent Filopodial Shortening in Mouse Neurons

Early postnatal anesthesia causes long-lasting learning and memory impairment in rodents, however, evidence for a specific neurotoxic effect on early synaptogenesis has not been demonstrated. Drebrin A is an actin binding protein whose localization in dendritic protrusions serves an important role i...

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Bibliographic Details
Main Authors: Zimering, Jeffrey H., Dong, Yuanlin, Fang, Fang, Huang, Lining, Zhang, Yiying, Xie, Zhongcong
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956198/