Development of AR-V7 as a putative treatment selection marker for metastatic castration-resistant prostate cancer

Prostate cancer cells demonstrate a remarkable “addiction” to androgen receptor (AR) signaling in all stages of disease progression. As such, suppression of AR signaling remains the therapeutic goal in systemic treatment of prostate cancer. A number of molecular alterations arise in patients treated...

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Bibliographic Details
Main Author: Luo, Jun
Format: Online
Language:English
Published: Medknow Publications & Media Pvt Ltd 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955182/