Development of AR-V7 as a putative treatment selection marker for metastatic castration-resistant prostate cancer
Prostate cancer cells demonstrate a remarkable “addiction” to androgen receptor (AR) signaling in all stages of disease progression. As such, suppression of AR signaling remains the therapeutic goal in systemic treatment of prostate cancer. A number of molecular alterations arise in patients treated...
Main Author: | |
---|---|
Format: | Online |
Language: | English |
Published: |
Medknow Publications & Media Pvt Ltd
2016
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955182/ |