Label-free CEST MRI Detection of Citicoline-Liposome Drug Delivery in Ischemic Stroke

ABSTRACT Citicoline (CDPC) is a natural supplement with well-documented neuroprotective effects in the treatment of neurodegenerative diseases. In the present study, we sought to exploit citicoline as a theranostic agent with its inherent chemical exchange saturation transfer (CEST) MRI signal, whic...

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Bibliographic Details
Main Authors: Liu, Huanling, Jablonska, Anna, Li, Yuguo, Cao, Suyi, Liu, Dexiang, Chen, Hanwei, Van Zijl, Peter CM, Bulte, Jeff W.M., Janowski, Miroslaw, Walczak, Piotr, Liu, Guanshu
Format: Online
Language:English
Published: Ivyspring International Publisher 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955057/