Profile of MMP and TIMP Expression in Human Pancreatic Stellate Cells: Regulation by IL-1α and TGFβ and Implications for Migration of Pancreatic Cancer Cells1
Pancreatic ductal adenocarcinoma is characterized by a prominent fibroinflammatory stroma with both tumor-promoting and tumor-suppressive functions. The pancreatic stellate cell (PSC) is the major cellular stromal component and the main producer of extracellular matrix proteins, including collagens,...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Neoplasia Press
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954934/ |