Mitochondrial Complex I Is a Global Regulator of Secondary Metabolism, Virulence and Azole Sensitivity in Fungi

Recent estimates of the global burden of fungal disease suggest that that their incidence has been drastically underestimated and that mortality may rival that of malaria or tuberculosis. Azoles are the principal class of antifungal drug and the only available oral treatment for fungal disease. Rece...

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Bibliographic Details
Main Authors: Bromley, Mike, Johns, Anna, Davies, Emma, Fraczek, Marcin, Mabey Gilsenan, Jane, Kurbatova, Natalya, Keays, Maria, Kapushesky, Misha, Gut, Marta, Gut, Ivo, Denning, David W., Bowyer, Paul
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954691/