Andrographolide derivative AL-1 ameliorates TNBS-induced colitis in mice: involvement of NF-кB and PPAR-γ signaling pathways

Andrographolide is a traditional herb medicine, widely used in Asia for conditions involving inflammation. The andrographlide-lipoic acid conjugate, AL-1, has been found being able to alleviate inflammation in our previous reports. Although the anti-inflammatory activity of AL-1 contributes to its c...

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Bibliographic Details
Main Authors: Yang, Yali, Yan, Hui, Jing, Mei, Zhang, Zaijun, Zhang, Gaoxiao, Sun, Yewei, Shan, Luchen, Yu, Pei, Wang, Yuqiang, Xu, Lipeng
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951727/