Quantification of Somatic Chromosomal Rearrangements in Circulating Cell-Free DNA from Ovarian Cancers

Recently, the use of a liquid biopsy has shown promise in monitoring tumor burden. While point mutations have been extensively studied, chromosomal rearrangements have demonstrated greater tumor specificity. Such rearrangements can be identified in the tumor and subsequently detected in the plasma o...

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Bibliographic Details
Main Authors: Harris, Faye R., Kovtun, Irina V., Smadbeck, James, Multinu, Francesco, Jatoi, Aminah, Kosari, Farhad, Kalli, Kimberly R., Murphy, Stephen J., Halling, Geoffrey C., Johnson, Sarah H., Liu, Minetta C., Mariani, Andrea, Vasmatzis, George
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951715/