Nickel chloride (NiCl2) induces endoplasmic reticulum (ER) stress by activating UPR pathways in the kidney of broiler chickens

It has been known that overexposure to Ni can induce nephrotoxicity. However, the mechanisms of underlying Ni nephrotoxicity are still elusive, and also Ni- and Ni compound-induced ER stress has been not reported in vivo at present. Our aim was to use broiler chickens as animal model to test whether...

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Bibliographic Details
Main Authors: Guo, Hongrui, Cui, Hengmin, Peng, Xi, Fang, Jing, Zuo, Zhicai, Deng, Junliang, Wang, Xun, Wu, Bangyuan, Chen, Kejie, Deng, Jie
Format: Online
Language:English
Published: Impact Journals LLC 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951229/