The HIV glycan shield as a target for broadly neutralizing antibodies
The HIV envelope glycoprotein (Env) is the sole target for HIV broadly neutralizing antibodies (bnAbs). HIV Env is one of the most heavily glycosylated proteins known, with approximately half of its mass consisting of host‐derived N‐linked glycans. The high density of glycans creates a shield that i...
| Main Author: | |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
John Wiley and Sons Inc.
2015
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950053/ |