Associations between polygenic risk for schizophrenia and brain function during probabilistic learning in healthy individuals

A substantial proportion of schizophrenia liability can be explained by additive genetic factors. Risk profile scores (RPS) directly index risk using a summated total of common risk variants weighted by their effect. Previous studies suggest that schizophrenia RPS predict alterations to neural netwo...

Full description

Bibliographic Details
Main Authors: Lancaster, Thomas M., Ihssen, Niklas, Brindley, Lisa M., Tansey, Katherine E., Mantripragada, Kiran, O'Donovan, Michael C., Owen, Michael J., Linden, David E.J.
Format: Online
Language:English
Published: John Wiley and Sons Inc. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949629/