The genetic tumor background is an important determinant for heterogeneous MYCN‐amplified neuroblastoma

The genetic tumor background is an important determinant for heterogeneous MYCN‐amplified neuroblastoma

Amplification of MYCN is the signature genetic aberration of 20–25% of neuroblastoma and a stratifying marker associated with aggressive tumor behavior. The detection of heterogeneous MYCN amplification (hetMNA) poses a diagnostic dilemma due to the uncertainty of its relevance to tumor behavior. He...

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Bibliographic Details
Main Authors: Bogen, Dominik, Brunner, Clemens, Walder, Diana, Ziegler, Andrea, Abbasi, Reza, Ladenstein, Ruth L., Noguera, Rosa, Martinsson, Tommy, Amann, Gabriele, Schilling, Freimut H., Ussowicz, Marek, Benesch, Martin, Ambros, Peter F., Ambros, Inge M.
Format: Online
Language:English
Published: John Wiley and Sons Inc. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949549/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949549/

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