Structural and functional insights into IZUMO1 recognition by JUNO in mammalian fertilization

Structural and functional insights into IZUMO1 recognition by JUNO in mammalian fertilization

Sperm–egg fusion is the critical step in mammalian fertilization, and requires the interaction between IZUMO1 on the sperm surface and JUNO (also known as folate receptor (FR) 4 or IZUMO1R) on the egg surface. Whereas other FRs bind and uptake folates, JUNO binds IZUMO1 and establishes the cell–cell...

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Bibliographic Details
Main Authors: Kato, Kazuki, Satouh, Yuhkoh, Nishimasu, Hiroshi, Kurabayashi, Arisa, Morita, Junko, Fujihara, Yoshitaka, Oji, Asami, Ishitani, Ryuichiro, Ikawa, Masahito, Nureki, Osamu
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947182/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947182/

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